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Benedryl (Diphenhydramine) and fertility

So, I found out something very interesting lately. I have really bad insomnia due to anxiety and I switched to benedryl as a sleep aid because it is safe and my other medicine was not. Well, since benedryl dries up mucous membranes, this also includes your cervix and cervical mucous. I was not getting the EWCM very much. So this cycle I stopped the benedryl during my entire fertile period and wow what a difference. In fact, I almost thought I was going to have another period mid cycle, but I was glad I didn't. This is just something to think about whiile we are TTC. We need the CM to be fertile during ovulation because without it we have a very decreased chance of concieving. I suggest you all make sure you aren't taking any other allergy medicines either if you are having difficulty because it has the same effects as well.


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2 Replies • 11 years ago


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Thank you so much for this post, I couldn't figure out why I was dry cause normaly I have alot cm. But when I got a sore throat followed by a running & stuffy nose, and it went on for about a week & half, just yesterday I took benedryl and even tho I am cleared from the stuffy & running nose I have become very dry. So I'm glad you posted this cause I did not know about that detail while ttc.

11 years ago


Glad I could help!


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11 years ago • Post starter


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