Community post

dinaak- I have never seen a positive that wasn't from a trigger shot, so I can't speak to the fading in and out of the line. That must be really frustrating. I just wanted to stop by and answer the one question I could- I have done vaginal progesterone suppositories during my last couple of 2wws and did not start af while on them. After my transfer this month we will be using progesterone injections instead of suppositories.

I finally conceived my daughter on my 6th ivf cycle. On 3 other cycles I experienced chemicals or early losses. Yes, you can have a chemical, get light positives in hpts before beta hcg and then a negative beta hcg. My numbers were very low on 2 of my chemicals, between 5 and 9, and my hpts were showing lines. They are more sensitive than they advertise.

The winning combo for me on my 6th attempt was an endometrial scratch the month before, a 30 day round of antibiotics before transfer, intramuscular estradiol til 11 weeks, intramuscular progesterone til 11 weeks, crinone (progesterone suppository gel) til 14 weeks, baby aspirin til 11 weeks, lovenox (blood thinner) my entire pregnancy and prednisolone (a steroid) til 9 weeks. I had to take double the normal progesterone! Also, one of my embryos was already hatching at transfer which I didn't have happen before.

Have you been tested for immune or clotting issues? That was my problem and I had a lot of trouble getting a strong implantation which led to very early miscarriages or chemicals.

There is a strange rule in my country that you have to have 3 CP or other early miscarriages for doctor to advise you to do these imune and other things.
By now I had 1 official CP.
And these 2 "unofficial" :)
That would be 3 but I'm not sure it will work because these unofficial ones.
I mean I will have to talk to him and convince him somehow maybe.
Baby aspirin is something that is given to everybody just as precaution, but I'm not sure it does much good/is strong enough if there is a problem with clotting.

My doctor was reluctant to test and treat me for nk cells, immune issues and clotting issues because they are kind of rare. I pretty much insisted and she finally caved. She was like I don't think that's the problem but since it's your last ivf we can try it. She already figured out that I had pcos, uterine polyps and my husband had a low count so she didn't she the sense of looking for more problems since we already found problems. But we did have more problems, treated them and it worked! I was going to move on to surrogacy on the next round.

Do some research on those issues and if you think you may have 1 or more go to your doctor armed with all the info. Think of things you have experienced your whole life, not just when ttcing, and see if any "symptoms" that you may not have thought were symptoms start popping up. They haven't known you your whole life so you might make connections that they haven't. For me some warning bells were bruising mysteriously and easily my whole life which pointed to clotting issues. And I was very rarely ever sick, even working in a school with a bunch of germ spreading lil monsters lol, which pointed to a strong immune system. Which is great pretty much all the time, just not when an embryo that is half "foreign" dna is trying to attach to you and your body tries fighting it instead.

mnor0406- a close friend of mine was in the same boat. She couldn't conceive and experienced recurrent mcs. Finally she combined ivf with PGS NGS and got pregnant.